BDBM190981 US10077266, Example 94::US9181249, 94::US9708313, 94
SMILES: COc1ccc(OC2CCN(CC2)c2nc3CCN(Cc3nc2NC2CCC2)C(C)=O)c(F)c1
InChI Key: InChIKey=FWBUWGUMMSYEGD-UHFFFAOYSA-N
Data: 3 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
G-protein coupled receptor 6 (Homo sapiens (Human)) | BDBM190981![]() (US10077266, Example 94 | US9181249, 94 | US9708313...) | UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 0.0199 | n/a | n/a | n/a | n/a | n/a | 37 |
Takeda Pharmaceutical Co., Ltd US Patent | Assay Description This cell based assay measures the ability of compounds to inhibit the constitutive cAMP activity of GPR6 receptor expressed in CHO-K1 cells. CHO cel... | US Patent US9181249 (2015) BindingDB Entry DOI: 10.7270/Q2HM577D | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
G-protein coupled receptor 6 (Homo sapiens (Human)) | BDBM190981![]() (US10077266, Example 94 | US9181249, 94 | US9708313...) | UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 1.99E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Pharmaceutical Co., Ltd US Patent | Assay Description Inhibition of cAMP Activity of GPR6 In Vitro AssayThis cell based assay measures the ability of compounds to inhibit the constitutive cAMP activity o... | US Patent US9708313 (2017) BindingDB Entry DOI: 10.7270/Q2ZP4858 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
G-protein coupled receptor 6 (Homo sapiens (Human)) | BDBM190981![]() (US10077266, Example 94 | US9181249, 94 | US9708313...) | UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 1.99E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Pharmaceutical Co., Ltd US Patent | Assay Description This cell based assay measures the ability of compounds to inhibit the constitutive cAMP activity of GPR6 receptor expressed in CHO-K1 cells. CHO cel... | US Patent US10077266 (2018) BindingDB Entry DOI: 10.7270/Q2T155PB | |||||||||||
More data for this Ligand-Target Pair |