BDBM190989 US10077266, Example 102::US9181249, 102::US9708313, 102

SMILES CO[C@@H](C)C(=O)N1CCc2nc(N3CCC(CC3)Oc3ccc(F)cc3F)c(NCC(F)F)nc2C1

InChI Key InChIKey=RDXSNOSVIFKOPG-AWEZNQCLSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 190989   

TargetG-protein coupled receptor 6(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM190989(US10077266, Example 102 | US9181249, 102 | US97083...)
Affinity DataIC50:  0.111nMT: 2°CAssay Description:This cell based assay measures the ability of compounds to inhibit the constitutive cAMP activity of GPR6 receptor expressed in CHO-K1 cells. CHO cel...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetG-protein coupled receptor 6(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM190989(US10077266, Example 102 | US9181249, 102 | US97083...)
Affinity DataIC50:  1.11E+5nMAssay Description:Inhibition of cAMP Activity of GPR6 In Vitro AssayThis cell based assay measures the ability of compounds to inhibit the constitutive cAMP activity o...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetG-protein coupled receptor 6(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM190989(US10077266, Example 102 | US9181249, 102 | US97083...)
Affinity DataIC50:  1.11E+5nMAssay Description:This cell based assay measures the ability of compounds to inhibit the constitutive cAMP activity of GPR6 receptor expressed in CHO-K1 cells. CHO cel...More data for this Ligand-Target Pair
In DepthDetails US Patent