BDBM191002 US10077266, Example 115::US9181249, 115::US9708313, 115

SMILES CC1Cc2nc(NCC(F)F)c(nc2CN1C(=O)C1CC1)N1CCC(CC1)Oc1ccc(F)cc1F

InChI Key InChIKey=RKCKCWRACZCCFE-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 191002   

TargetG-protein coupled receptor 6(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM191002(US10077266, Example 115 | US9181249, 115 | US97083...)
Affinity DataIC50:  0.0239nMT: 2°CAssay Description:This cell based assay measures the ability of compounds to inhibit the constitutive cAMP activity of GPR6 receptor expressed in CHO-K1 cells. CHO cel...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetG-protein coupled receptor 6(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM191002(US10077266, Example 115 | US9181249, 115 | US97083...)
Affinity DataIC50:  2.39E+4nMAssay Description:Inhibition of cAMP Activity of GPR6 In Vitro AssayThis cell based assay measures the ability of compounds to inhibit the constitutive cAMP activity o...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetG-protein coupled receptor 6(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM191002(US10077266, Example 115 | US9181249, 115 | US97083...)
Affinity DataIC50:  2.39E+4nMAssay Description:This cell based assay measures the ability of compounds to inhibit the constitutive cAMP activity of GPR6 receptor expressed in CHO-K1 cells. CHO cel...More data for this Ligand-Target Pair
In DepthDetails US Patent