BDBM191346 US9181272, 116

SMILES NC(=O)N1CCCc2cc(cnc12)-c1cncc(NCc2ccccc2)c1

InChI Key InChIKey=VGEZWMWNOPCGID-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 191346   

TargetCytochrome P450 family 11 subfamily B member 2(Cercopithecus sabaeus)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM191346(US9181272, 116)
Affinity DataIC50:  3.5nMpH: 7.4Assay Description:The aldosterone synthase inhibition assay employs cynomolgus adrenal gland mitochondria as the source of aldosterone synthase (CYP11B2). Mitochondr...More data for this Ligand-Target Pair
In DepthDetails US Patent