BDBM19137 tert-butyl N-[(1S)-1-(tert-butylcarbamoyl)-6-sulfanylhexyl]carbamate::thiolate analogue, 19a

SMILES CC(C)(C)NC(=O)[C@H](CCCCCS)NC(=O)OC(C)(C)C

InChI Key InChIKey=FYJYSSQDWGZNHS-LBPRGKRZSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 19137   

TargetHistone deacetylase 6(Mus musculus)
Nagoya City University

LigandPNGBDBM19137(tert-butyl N-[(1S)-1-(tert-butylcarbamoyl)-6-sulfa...)
Affinity DataIC50:  71nMpH: 8.0 T: 2°CAssay Description:The enzyme activity was assayed using recombinant HDAC and [3H] acetyl-labeled histones as substrate. The released [3H]acetic acid was extracted and ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
Nagoya City University

LigandPNGBDBM19137(tert-butyl N-[(1S)-1-(tert-butylcarbamoyl)-6-sulfa...)
Affinity DataIC50:  1.90E+3nMAssay Description:The enzyme activity was assayed using recombinant HDAC and [3H] acetyl-labeled histones as substrate. The released [3H]acetic acid was extracted and ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Nagoya City University

LigandPNGBDBM19137(tert-butyl N-[(1S)-1-(tert-butylcarbamoyl)-6-sulfa...)
Affinity DataIC50:  3.00E+3nMpH: 8.0 T: 2°CAssay Description:The enzyme activity was assayed using recombinant HDAC and [3H] acetyl-labeled histones as substrate. The released [3H]acetic acid was extracted and ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed