BDBM191581 6-(2,4-dichlorophenyl)pteridine-2,4,7-triamine (25)

SMILES Nc1nc(N)c2nc(c(N)nc2n1)-c1ccc(Cl)cc1Cl

InChI Key InChIKey=PBXKIZZVZCGAJV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 191581   

TargetCasein kinase I isoform epsilon(Homo sapiens (Human))
Max Planck Institute of Molecular Physiology

LigandPNGBDBM191581(6-(2,4-dichlorophenyl)pteridine-2,4,7-triamine (25...)
Affinity DataIC50:  4.30E+3nMpH: 7.5Assay Description:A stock solution of 5 % DMSO (BioReagent for molecular biology, Sigma Aldrich) in water was prepared. The CK1 substrate peptide RRKDLHDDEEDEAMSITA (J...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCasein kinase I isoform alpha(Homo sapiens (Human))
Max Planck Institute of Molecular Physiology

LigandPNGBDBM191581(6-(2,4-dichlorophenyl)pteridine-2,4,7-triamine (25...)
Affinity DataIC50:  5.56E+4nMAssay Description:Single-point measurements analyses and subsequent dose-dependent investigations of selected pteridine derivatives for inhibition of CK1α were pe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed