BDBM191770 US10669227, Compound 7::US11608309, Compound 7::US9187406, Compound 7
SMILES Oc1ccc(\C=C\C(=O)C(C(=O)Nc2ccccc2)C(=O)\C=C\c2ccc(O)cc2)cc1
InChI Key InChIKey=ZPZMHBPRQOJARQ-OTYYAQKOSA-N
Data 6 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 191770
Target72 kDa type IV collagenase(Homo sapiens (Human))
The Research Foundation Of State University Of New York
US Patent
The Research Foundation Of State University Of New York
US Patent
Affinity DataIC50: 1.25E+5nMT: 2°CAssay Description:It has been observed that 50 and 100 μM concentrations of curcumin decreased TNFα production by endotoxin-stimulated human monocytes (HMs) ...More data for this Ligand-Target Pair
TargetCollagenase 3(Homo sapiens (Human))
The Research Foundation Of State University Of New York
US Patent
The Research Foundation Of State University Of New York
US Patent
Affinity DataIC50: <1.00E+3nMT: 2°CAssay Description:It has been observed that 50 and 100 μM concentrations of curcumin decreased TNFα production by endotoxin-stimulated human monocytes (HMs) ...More data for this Ligand-Target Pair
TargetCollagenase 3(Homo sapiens (Human))
The Research Foundation Of State University Of New York
US Patent
The Research Foundation Of State University Of New York
US Patent
Affinity DataIC50: <1.00E+3nMAssay Description:Table 10: The efficacy of MMP-2 inhibition was as follows: compound 6>compound 7>compound 8. Although compound 6 showed similar efficacy as curcumin ...More data for this Ligand-Target Pair
TargetCollagenase 3(Homo sapiens (Human))
The Research Foundation Of State University Of New York
US Patent
The Research Foundation Of State University Of New York
US Patent
Affinity DataIC50: <1.00E+3nMAssay Description:It has been observed that 50 and 100 μM concentrations of curcumin decreased TNFα production by endotoxin-stimulated human monocytes (HMs) ...More data for this Ligand-Target Pair
Target72 kDa type IV collagenase(Homo sapiens (Human))
The Research Foundation Of State University Of New York
US Patent
The Research Foundation Of State University Of New York
US Patent
Affinity DataIC50: 1.25E+5nMAssay Description:Table 10: The efficacy of MMP-2 inhibition was as follows: compound 6>compound 7>compound 8. Although compound 6 showed similar efficacy as curcumin ...More data for this Ligand-Target Pair
Target72 kDa type IV collagenase(Homo sapiens (Human))
The Research Foundation Of State University Of New York
US Patent
The Research Foundation Of State University Of New York
US Patent
Affinity DataIC50: 1.25E+5nMAssay Description:It has been observed that 50 and 100 μM concentrations of curcumin decreased TNFα production by endotoxin-stimulated human monocytes (HMs) ...More data for this Ligand-Target Pair