BDBM191880 US9187429, 5::US9187429, 6::US9187429, 7
SMILES CCC(=O)NC1CCCc2c1cncc2-c1ccc(cc1)C#N
InChI Key InChIKey=ITXORCJLPUUDIY-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 10 hits for monomerid = 191880
Affinity DataEC50: 760nMAssay Description:G-402 cells can be obtained from ATCC(CRL-1440) and were originally
derived from a renal leiomyoblastoma. The expression plasmids contains
the ORF ...More data for this Ligand-Target Pair
Affinity DataEC50: 1.17E+4nMAssay Description:G-402 cells can be obtained from ATCC(CRL-1440) and were originally
derived from a renal leiomyoblastoma. The expression plasmids contains
the ORF ...More data for this Ligand-Target Pair
Affinity DataEC50: 263nMAssay Description:G-402 cells can be obtained from ATCC(CRL-1440) and were originally
derived from a renal leiomyoblastoma. The expression plasmids contains
the ORF ...More data for this Ligand-Target Pair
Affinity DataEC50: 25nMAssay Description:G-402 cells can be obtained from ATCC(CRL-1440) and were originally
derived from a renal leiomyoblastoma. The expression plasmids contains
the ORF ...More data for this Ligand-Target Pair
TargetCytochrome P450 2C9(Homo sapiens (Human))
Roche Pharma Research And Early Development (Pred)
Curated by ChEMBL
Roche Pharma Research And Early Development (Pred)
Curated by ChEMBL
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
Affinity DataEC50: 10nMAssay Description:G-402 cells can be obtained from ATCC(CRL-1440) and were originally
derived from a renal leiomyoblastoma. The expression plasmids contains
the ORF ...More data for this Ligand-Target Pair
TargetCytochrome P450 3A4(Homo sapiens (Human))
Roche Pharma Research And Early Development (Pred)
Curated by ChEMBL
Roche Pharma Research And Early Development (Pred)
Curated by ChEMBL
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 25nMAssay Description:Inhibition of human CYP11B2 expressed in human renal leiomyoblastoma cells using 11-deoxycorticosterone as substrate assessed as formation of aldoste...More data for this Ligand-Target Pair
TargetCytochrome P450 2D6(Homo sapiens (Human))
Roche Pharma Research And Early Development (Pred)
Curated by ChEMBL
Roche Pharma Research And Early Development (Pred)
Curated by ChEMBL
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
Affinity DataEC50: 942nMAssay Description:G-402 cells can be obtained from ATCC(CRL-1440) and were originally
derived from a renal leiomyoblastoma. The expression plasmids contains
the ORF ...More data for this Ligand-Target Pair