BDBM191908 US9187429, 43

SMILES CCC(=O)NC1CCCc2c1cncc2-c1cc(F)c(F)cc1F

InChI Key InChIKey=XBIIVZQGMZWYPK-UHFFFAOYSA-N

Data  1 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 191908   

TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM191908(US9187429, 43)
Affinity DataEC50:  1.15E+3nMAssay Description:G-402 cells can be obtained from ATCC(CRL-1440) and were originally derived from a renal leiomyoblastoma. The expression plasmids contains the ORF ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Roche Pharma Research And Early Development (Pred)

Curated by ChEMBL
LigandPNGBDBM191908(US9187429, 43)
Affinity DataIC50:  27nMAssay Description:Inhibition of human CYP11B2 expressed in human renal leiomyoblastoma cells using 11-deoxycorticosterone as substrate assessed as formation of aldoste...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Roche Pharma Research And Early Development (Pred)

Curated by ChEMBL
LigandPNGBDBM191908(US9187429, 43)
Affinity DataEC50:  27nMAssay Description:G-402 cells can be obtained from ATCC(CRL-1440) and were originally derived from a renal leiomyoblastoma. The expression plasmids contains the ORF ...More data for this Ligand-Target Pair
In DepthDetails US Patent