BDBM192650 N’-(phenylmethylene)benzohydrazide (1a)

SMILES O=C(N\N=C\c1ccccc1)c1ccccc1

InChI Key InChIKey=RISHSDLMXPLIHT-RVDMUPIBSA-N

Data  3 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 192650   

TargetCathepsin L(Capra hircus (Goat))
Kurukshetra University

LigandPNGBDBM192650(N’-(phenylmethylene)benzohydrazide (1a))
Affinity DataKi:  13nM ΔG°:  -11.2kcal/molepH: 5.0 T: 2°CAssay Description:The proteolytic activity was estimated at pH 5.0, 37 °C using 0.1 M acetate buffer as the incubation medium. The homogenate prepared above was incuba...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Capra hircus (Goat))
Kurukshetra University

LigandPNGBDBM192650(N’-(phenylmethylene)benzohydrazide (1a))
Affinity DataKi:  290nM ΔG°:  -9.27kcal/molepH: 5.0 T: 2°CAssay Description:The proteolytic activity was estimated at pH 5.0, 37 °C using 0.1 M acetate buffer as the incubation medium. The homogenate prepared above was incuba...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin H(Capra hircus (Goat))
Kurukshetra University

LigandPNGBDBM192650(N’-(phenylmethylene)benzohydrazide (1a))
Affinity DataKi:  2.14E+3nM ΔG°:  -8.04kcal/molepH: 5.0 T: 2°CAssay Description:The proteolytic activity was estimated at pH 5.0, 37 °C using 0.1 M acetate buffer as the incubation medium. The homogenate prepared above was incuba...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Coxsackievirus B3 (strain Nancy))
Gwangju Institute Of Science And Technology (Gist)

Curated by ChEMBL
LigandPNGBDBM192650(N’-(phenylmethylene)benzohydrazide (1a))
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of recombinant Coxsackievirus B3 3C protease expressed in Escherichia coli BL21 (DE3) preincubated for 5 mins followed by addition of NMA-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed