BDBM192662 2-phenyl-5-(2-chlorophenyl)-1,3,4-oxadiazole (2c)

SMILES Clc1ccccc1-c1nnc(o1)-c1ccccc1

InChI Key InChIKey=JXVBNSUTUSYBNW-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 192662   

TargetCathepsin L(Capra hircus (Goat))
Kurukshetra University

LigandPNGBDBM192662(2-phenyl-5-(2-chlorophenyl)-1,3,4-oxadiazole (2c))
Affinity DataKi:  92.1nM ΔG°:  -9.98kcal/molepH: 5.0 T: 2°CAssay Description:The proteolytic activity was estimated at pH 5.0, 37 °C using 0.1 M acetate buffer as the incubation medium. The homogenate prepared above was incuba...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin H(Capra hircus (Goat))
Kurukshetra University

LigandPNGBDBM192662(2-phenyl-5-(2-chlorophenyl)-1,3,4-oxadiazole (2c))
Affinity DataKi:  560nM ΔG°:  -8.87kcal/molepH: 5.0 T: 2°CAssay Description:The proteolytic activity was estimated at pH 5.0, 37 °C using 0.1 M acetate buffer as the incubation medium. The homogenate prepared above was incuba...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Capra hircus (Goat))
Kurukshetra University

LigandPNGBDBM192662(2-phenyl-5-(2-chlorophenyl)-1,3,4-oxadiazole (2c))
Affinity DataKi:  1.62E+3nM ΔG°:  -8.21kcal/molepH: 5.0 T: 2°CAssay Description:The proteolytic activity was estimated at pH 5.0, 37 °C using 0.1 M acetate buffer as the incubation medium. The homogenate prepared above was incuba...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed