BDBM192820 US9187487, 86

SMILES CC(C)(C)C(=O)c1c[nH]c2ncc(Nc3ccc(C=C(C#N)c4ccno4)cc3)nc12

InChI Key InChIKey=WHFXQLDSMZYCSJ-XNTDXEJSSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 192820   

TargetTyrosine-protein kinase JAK3 [781-1124](Homo sapiens (Human))
Principia Biopharma

US Patent
LigandPNGBDBM192820(US9187487, 86)
Affinity DataIC50:  35.1nMpH: 7.5 T: 2°CAssay Description:Phosphorylation of the appropriate peptide substrate (fluorescently labeled Srctide) by recombinant JAK3 (catalytic domain, aa 781-1124) was measured...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent