BDBM192947 US9670204, 142 (R)-2-((2-ethyl-6-(1-(2-(3-hydroxypyrrolidin-1-yl)-2-oxoethyl)piperidin-4-yl)imidazo[1,2-a]pyridin-3-yl)(methyl)amino)-4-(4-fluorophenyl)thiazole-5-carbonitrile

SMILES CCc1nc2ccc(cn2c1N(C)c1nc(c(s1)[N+]#[C-])-c1ccc(F)cc1)C1CCN(CC(=O)N2CC[C@@H](O)C2)CC1

InChI Key InChIKey=KEWVYNVXZMUYFG-XMMPIXPASA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 192947   

TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Galapagos

US Patent
LigandPNGBDBM192947(US9670204, 142 (R)-2-((2-ethyl-6-(1-(2-(3-hydroxyp...)
Affinity DataIC50:  50nMpH: 8.5 T: 2°CAssay Description:Compound IC50 values are determined in a hENPP2 (UniProtKB/SwissProt Sequence ref Q13822) biochemical assay using LPC as substrate. 5 μL of a di...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent