BDBM193013 US9193726, 1

SMILES Cc1cn(cn1)-c1ccc2C(=O)N(CCn2c1=O)[C@@H]1CC[C@H]1Oc1ccccc1C(F)(F)F

InChI Key InChIKey=XFUCEQUGDGIWEL-OXQOHEQNSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 193013   

TargetPresenilin-1(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM193013(US9193726, 1)
Affinity DataIC50:  211nMT: 2°CAssay Description:The ability of compounds to modulate production of amyloid beta protein Abeta(1-42) was determined using human WT-APP overexpressing CHO cells. Cel...More data for this Ligand-Target Pair
In DepthDetails US Patent