BDBM193392 US9670208, Example 115

SMILES CC[C@H](C)Cc1nnc2cc(ccn12)-c1ccnc(Nc2ccnn2C)n1

InChI Key InChIKey=ZKROPNQERHXKAI-ZDUSSCGKSA-N

Data  1 IC50

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 193392   

TargetMitogen-activated protein kinase 1 [8-360](Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM193392(US9670208, Example 115)
Affinity DataIC50:  2.80nMpH: 7.3Assay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails US Patent