BDBM193402 US9670208, Example 140 (2,6-difluorophenyl)(2-(7-(2-((tetrahydro-2H-pyran-4-yl)amino)pyrimidin-4-yl)-[1,2,4]triazolo[4,3-a]pyridin-3-yl)morpholino)methanone

SMILES Fc1cccc(F)c1C(=O)N1CCOC(C1)c1nnc2cc(ccn12)-c1ccnc(NC2CCOCC2)n1

InChI Key InChIKey=DOJAVRISNHIQAC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 193402   

TargetMitogen-activated protein kinase 1 [8-360](Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM193402(US9670208, Example 140 (2,6-difluorophenyl)(2-(7-(...)
Affinity DataIC50:  7.5nMpH: 7.3Assay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent