BDBM193864 3-(4-((Butylamino)methyl)-5-thioxo-4,5-dihydro-1,3,4-oxadiazol- 2-yl)-2H-chromen-2-one (11b)

SMILES CCCCNCn1nc(oc1=S)-c1cc2ccccc2oc1=O

InChI Key InChIKey=BZJMDPNCAIEPIJ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 193864   

TargetAldo-keto reductase family 1 member A1(Bos taurus (Cattle))
Comsats Institute Of Information Technology

LigandPNGBDBM193864(3-(4-((Butylamino)methyl)-5-thioxo-4,5-dihydro-1,3...)
Affinity DataIC50:  3.36E+3nMpH: 6.2Assay Description:The assay results were obtained at 340 nm and ALR1 inhibitory activity was measured with the absorbance change at this respective wavelength. Each we...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Bos taurus)
Abbottabad University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM193864(3-(4-((Butylamino)methyl)-5-thioxo-4,5-dihydro-1,3...)
Affinity DataIC50:  3.36E+3nMAssay Description:Inhibition of bovine kidney ALR1 using D-glucoronic acid as substrate preincubated for 5 mins followed by NADPH addition measured after 10 mins by UV...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1 [K65Q](Bos taurus (Cattle))
Comsats Institute Of Information Technology

LigandPNGBDBM193864(3-(4-((Butylamino)methyl)-5-thioxo-4,5-dihydro-1,3...)
Affinity DataIC50:  5.75E+4nMAssay Description:The activity of ALR2 enzyme was determined at 340 nm in UV spectrophotometer that depends upon the measurement of NADPH consumption. Each well of the...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed