BDBM194349 US9200016, 31::US9902710, Compound 31
SMILES CCOc1cc2c(Cc3cnc4ccccc4c3)cncc2cc1OC
InChI Key InChIKey=GGXCSFDRJUWEJW-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 194349
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Exonhit Therapeutics
US Patent
Exonhit Therapeutics
US Patent
Affinity DataIC50: 92nMAssay Description:The phosphodiesterase assay was developed using the LANCE® cAMP kit (PerkinElmer). The assay buffer contained HBSS with 5 mM HEPES, 0.1% BSA, and 1.5...More data for this Ligand-Target Pair
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Exonhit Therapeutics
US Patent
Exonhit Therapeutics
US Patent
Affinity DataIC50: 92nMpH: 7.4 T: 2°CAssay Description:The phosphodiesterase assay was developed using the LANCE cAMP kit
(PerkinElmer). The assay buffer contained HBSS with 5 mM HEPES, 0.1%
BSA, and 1....More data for this Ligand-Target Pair