BDBM194436 US9200016, 118::US9902710, Compound 118

SMILES CCCc1ncc(Cc2ccc3cccc(OCCC([O-])=O)c3n2)c2cc(OC)c(OC)cc12

InChI Key InChIKey=WABZZNSLGKUEIK-UHFFFAOYSA-M

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 194436   

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Exonhit Therapeutics

US Patent
LigandPNGBDBM194436(US9200016, 118 | US9902710, Compound 118)
Affinity DataIC50:  2.30nMAssay Description:The phosphodiesterase assay was developed using the LANCE® cAMP kit (PerkinElmer). The assay buffer contained HBSS with 5 mM HEPES, 0.1% BSA, and 1.5...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Exonhit Therapeutics

US Patent
LigandPNGBDBM194436(US9200016, 118 | US9902710, Compound 118)
Affinity DataIC50:  2.30nMpH: 7.4 T: 2°CAssay Description:The phosphodiesterase assay was developed using the LANCE cAMP kit (PerkinElmer). The assay buffer contained HBSS with 5 mM HEPES, 0.1% BSA, and 1....More data for this Ligand-Target Pair
In DepthDetails US Patent