BDBM194502 US9200020, Table 3 compound 11

SMILES Nc1nc2n(CCN(CCP(O)(O)=O)CCP(O)(O)=O)c[nH]c2c(=O)[nH]1

InChI Key InChIKey=RSLKQFQEAUQNJX-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 194502   

TargetHypoxanthine-guanine phosphoribosyltransferase(Homo sapiens (Human))
The University Of Queensland

US Patent
LigandPNGBDBM194502(US9200020, Table 3 compound 11)
Affinity DataKi:  200nMpH: 7.4Assay Description:The Ki values were determined using a spectrophotometric assay at 25° C., 0.1 M Tris-HCl, 10 mM MgCl2, pH 7.4 (Keough, D. T.; Ng, A. L.; Winzor, D. J...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHypoxanthine-guanine-xanthine phosphoribosyltransferase(Plasmodium falciparum)
The University Of Queensland

US Patent
LigandPNGBDBM194502(US9200020, Table 3 compound 11)
Affinity DataKi:  300nMpH: 7.4Assay Description:The Ki values were determined using a spectrophotometric assay at 25° C., 0.1 M Tris-HCl, 10 mM MgCl2, pH 7.4 (Keough, D. T.; Ng, A. L.; Winzor, D. J...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHypoxanthine phosphoribosyltransferase(Plasmodium vivax)
The University Of Queensland

US Patent
LigandPNGBDBM194502(US9200020, Table 3 compound 11)
Affinity DataKi:  900nMpH: 7.4Assay Description:The Ki values were determined using a spectrophotometric assay at 25° C., 0.1 M Tris-HCl, 10 mM MgCl2, pH 7.4 (Keough, D. T.; Ng, A. L.; Winzor, D. J...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent