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BDBM19472 2-oxoacetic acid::Glyoxylate::Oxoethanoic acid::glyoxylic acid::oxaldehydic acid

SMILES: OC(=O)C=O

InChI Key: InChIKey=HHLFWLYXYJOTON-UHFFFAOYSA-N

Data: 1 KI  3 ITC

PDB links: 29 PDB IDs match this monomer.

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 19472   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Dihydrodipicolinate synthase


(Escherichia coli (strain K12))
BDBM19472
PNG
(2-oxoacetic acid | Glyoxylate | Oxoethanoic acid |...)
Show SMILES OC(=O)C=O
Show InChI InChI=1S/C2H2O3/c3-1-2(4)5/h1H,(H,4,5)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
Purchase

CHEBI
DrugBank
KEGG
MMDB
PC cid
PC sid
PDB
UniChem

Patents


Similars

Article
PubMed
1.60E+4n/an/an/an/an/an/an/an/a



University of Melbourne

Curated by ChEMBL


Assay Description
Inhibition of Escherichia coli DHDPS


Bioorg Med Chem 16: 9975-83 (2008)


Article DOI: 10.1016/j.bmc.2008.10.026
BindingDB Entry DOI: 10.7270/Q2FN1748
More data for this
Ligand-Target Pair

Activity Spreadsheet -- ITC Data from BindingDB

Found 3 hits for monomerid = 19472
Cell (A)Syringe (B)Cell
Links
Syringe
Links
Cell + Syr
Links
ΔG°
kcal/mole
-TΔS°
kcal/mole
ΔH°
kcal/mole
log KpHTemp
°C
Glyoxylate Regulatory Protein (C-AllR)

(Escherichia coli)
BDBM19472
JPEG
(2-oxoacetic acid | Glyoxylate | Oxoethanoic acid |...)
GoogleScholar
PDB
CHEBI
DrugBank
KEGG
MMDB
PC cid
PC sid
PDB
-1.067.20-8.195.047.4025



University of Toronto





J Biol Chem 282: 16476-91 (2007)

Acetate Operon Repressor (IclR)

(Escherichia coli)
BDBM19472
JPEG
(2-oxoacetic acid | Glyoxylate | Oxoethanoic acid |...)
GoogleScholar
PDB
CHEBI
DrugBank
KEGG
MMDB
PC cid
PC sid
PDB
-4.99-0.798-5.794.887.4025



University of Toronto





J Biol Chem 282: 16476-91 (2007)

Acetate Operon Repressor (C-IclR)

(Escherichia coli)
BDBM19472
JPEG
(2-oxoacetic acid | Glyoxylate | Oxoethanoic acid |...)
GoogleScholar
PDB
CHEBI
DrugBank
KEGG
MMDB
PC cid
PC sid
PDB
-8.091.96-10.16.087.4025



University of Toronto





J Biol Chem 282: 16476-91 (2007)