BDBM1949 (Alkylamino)piperidine BHAP Analog 5::2-N-cyclopropyl-2-N-[1-(1H-indol-2-ylcarbonyl)piperidin-4-yl]-3-N-(propan-2-yl)pyridine-2,3-diamine

SMILES CC(C)Nc1cccnc1N(C1CC1)C1CCN(CC1)C(=O)c1cc2ccccc2[nH]1

InChI Key InChIKey=FYFDKVGQAJSRPL-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 1949   

TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Upjohn

LigandPNGBDBM1949((Alkylamino)piperidine BHAP Analog 5 | 2-N-cyclopr...)
Affinity DataIC50:  700nMpH: 8.3 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [588-1127,Y768C]/[588-1147,Y768C](Human immunodeficiency virus type 1)
Upjohn

LigandPNGBDBM1949((Alkylamino)piperidine BHAP Analog 5 | 2-N-cyclopr...)
Affinity DataIC50:  2.31E+3nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [588-1027,P823L]/[588-1147,P823L](Human immunodeficiency virus type 1)
Upjohn

LigandPNGBDBM1949((Alkylamino)piperidine BHAP Analog 5 | 2-N-cyclopr...)
Affinity DataIC50:  590nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed