BDBM195005 US9206198, 66
SMILES CCC1CC2(CCN(C[C@H](O)c3ccc4C(=O)OCc4c3C)CC2)C(=O)N1C1=CC(=O)OC1
InChI Key InChIKey=OGTISSLCALEKCM-MRNPHLECSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 195005
TargetATP-sensitive inward rectifier potassium channel 1(Homo sapiens (Human))
Merck Sharp & Dohme
US Patent
Merck Sharp & Dohme
US Patent
Affinity DataIC50: 20nMpH: 7.4 T: 2°CAssay Description:Block of Kir1.1 (ROMK1) currents was examined by whole cell voltage
clamp (Hamill et. al. Pfluegers Archives 391:85-100 (1981)) using the
IonWorks ...More data for this Ligand-Target Pair
TargetATP-sensitive inward rectifier potassium channel 1(Homo sapiens (Human))
Merck Sharp & Dohme
US Patent
Merck Sharp & Dohme
US Patent
Affinity DataIC50: 10nMT: 2°CAssay Description:The ROMK channel functional thallium flux assay is performed in 384
wells, using the FLIPR-Tetra instrument. HEK-hKir1.1 cells are seeded in
Poly-D...More data for this Ligand-Target Pair