BDBM19548 (2S)-2-cyclohexyl-N-{2-[(4-methoxyphenyl)amino]ethyl}-2-[(3-methylphenyl)formamido]acetamide::arylaminoethyl amide, 5b

SMILES COc1ccc(NCCNC(=O)[C@@H](NC(=O)c2cccc(C)c2)C2CCCCC2)cc1

InChI Key InChIKey=VEUMPOBSVCGSCK-QHCPKHFHSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 19548   

TargetProcathepsin L(Homo sapiens (Human))
Gnf

LigandPNGBDBM19548((2S)-2-cyclohexyl-N-{2-[(4-methoxyphenyl)amino]eth...)
Affinity DataKi:  22nMAssay Description:The recombinant human cathepsin enzyme was preincubated with inhibitor for 20 minutes prior to addition of substrate. The substrate hydrolysis was mo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Gnf

LigandPNGBDBM19548((2S)-2-cyclohexyl-N-{2-[(4-methoxyphenyl)amino]eth...)
Affinity DataKi:  23nM ΔG°:  -10.8kcal/molepH: 5.5 T: 2°CAssay Description:The recombinant human cathepsin enzyme was preincubated with inhibitor for 20 minutes prior to addition of substrate. The substrate hydrolysis was mo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Gnf

LigandPNGBDBM19548((2S)-2-cyclohexyl-N-{2-[(4-methoxyphenyl)amino]eth...)
Affinity DataKi:  66nMAssay Description:The recombinant human cathepsin enzyme was preincubated with inhibitor for 20 minutes prior to addition of substrate. The substrate hydrolysis was mo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed