BDBM19555 (2S)-3-(2-chlorophenyl)-N-{2-[(4-methoxyphenyl)amino]ethyl}-2-[(3-methylphenyl)formamido]propanamide::arylaminoethyl amide, 5i

SMILES COc1ccc(NCCNC(=O)[C@H](Cc2ccccc2Cl)NC(=O)c2cccc(C)c2)cc1

InChI Key InChIKey=MMOQDAMRMLPVQY-DEOSSOPVSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 19555   

TargetProcathepsin L(Homo sapiens (Human))
Gnf

LigandPNGBDBM19555((2S)-3-(2-chlorophenyl)-N-{2-[(4-methoxyphenyl)ami...)
Affinity DataKi:  5nMAssay Description:The recombinant human cathepsin enzyme was preincubated with inhibitor for 20 minutes prior to addition of substrate. The substrate hydrolysis was mo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Gnf

LigandPNGBDBM19555((2S)-3-(2-chlorophenyl)-N-{2-[(4-methoxyphenyl)ami...)
Affinity DataKi:  35nM ΔG°:  -10.6kcal/molepH: 5.5 T: 2°CAssay Description:The recombinant human cathepsin enzyme was preincubated with inhibitor for 20 minutes prior to addition of substrate. The substrate hydrolysis was mo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Gnf

LigandPNGBDBM19555((2S)-3-(2-chlorophenyl)-N-{2-[(4-methoxyphenyl)ami...)
Affinity DataKi:  595nMAssay Description:The recombinant human cathepsin enzyme was preincubated with inhibitor for 20 minutes prior to addition of substrate. The substrate hydrolysis was mo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed