BDBM195898 US9670214, TABLE 10.11

SMILES NC(=O)CCn1ncc2c(Nc3ccc(OC(F)(F)F)cc3)ncnc12

InChI Key InChIKey=MQXBCNJRTVABLK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 195898   

TargetNon-specific protein-tyrosine kinase [T818I](Homo sapiens (Human))
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM195898(US9670214, TABLE 10.11)
Affinity DataIC50:  4.30E+3nMpH: 7.5Assay Description:In vitro kinase assays were carried out by using recombinant murine c-abl containing SH3, SH2 and kinase domains (residues 46-531) and full length im...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNon-specific protein-tyrosine kinase(Homo sapiens (Human))
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM195898(US9670214, TABLE 10.11)
Affinity DataIC50:  910nMpH: 7.5Assay Description:In vitro kinase assays were carried out by using recombinant murine c-abl containing SH3, SH2 and kinase domains (residues 46-531) and full length im...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent