BDBM196 A-74704::CHEMBL307193::benzyl N-[(1S)-1-{[(2S,4S)-4-[(2S)-2-{[(benzyloxy)carbonyl]amino}-3-methylbutanamido]-3-hydroxy-1,5-diphenylpentan-2-yl]carbamoyl}-2-methylpropyl]carbamate

SMILES CC(C)[C@H](NC(=O)OCc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)OCc1ccccc1)C(C)C

InChI Key InChIKey=GEANBHANAKKWSL-ZQWQDMLBSA-N

Data  1 KI  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 196   

TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Abbott Laboratories

LigandPNGBDBM196(A-74704 | CHEMBL307193 | benzyl N-[(1S)-1-{[(2S,4S...)
Affinity DataKi:  4.5nM ΔG°:  -11.6kcal/molepH: 4.7 T: 2°CAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-GABA-Ser-Gln-Tyr-P...More data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM196(A-74704 | CHEMBL307193 | benzyl N-[(1S)-1-{[(2S,4S...)
Affinity DataIC50:  3nMAssay Description:The compound was tested for its affinity against HIV-1 proteaseMore data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM196(A-74704 | CHEMBL307193 | benzyl N-[(1S)-1-{[(2S,4S...)
Affinity DataIC50:  3nMAssay Description:Inhibitory activity of the compound was evaluated against HIV-protease was evaluatedMore data for this Ligand-Target Pair