BDBM19642 (2R)-2-(cyclohexylmethyl)-4-(morpholin-4-yl)-4-oxo-N-(2-{[4-(trifluoromethoxy)phenyl]amino}ethyl)butanamide::succinamide peptidomimetic, 8

SMILES FC(F)(F)Oc1ccc(NCCNC(=O)[C@H](CC2CCCCC2)CC(=O)N2CCOCC2)cc1

InChI Key InChIKey=XLQGAYZYFHQOIR-LJQANCHMSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 19642   

TargetCathepsin S(Homo sapiens (Human))
Gnf

LigandPNGBDBM19642((2R)-2-(cyclohexylmethyl)-4-(morpholin-4-yl)-4-oxo...)
Affinity DataKi:  194nM ΔG°:  -9.52kcal/molepH: 5.5 T: 2°CAssay Description:The recombinant human cathepsin enzyme was preincubated with inhibitor for 20 minutes prior to addition of substrate. The substrate hydrolysis was mo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Gnf

LigandPNGBDBM19642((2R)-2-(cyclohexylmethyl)-4-(morpholin-4-yl)-4-oxo...)
Affinity DataKi: >3.00E+4nMAssay Description:The recombinant human cathepsin enzyme was preincubated with inhibitor for 20 minutes prior to addition of substrate. The substrate hydrolysis was mo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Gnf

LigandPNGBDBM19642((2R)-2-(cyclohexylmethyl)-4-(morpholin-4-yl)-4-oxo...)
Affinity DataKi: >1.00E+5nMAssay Description:The recombinant human cathepsin enzyme was preincubated with inhibitor for 20 minutes prior to addition of substrate. The substrate hydrolysis was mo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed