BDBM196727 (s)-2-(((2,5-difluorophenyl)amino)methyl)-5-(4-fluorophenyl)-7-methyl-6,7-dihydropyrazolo[1,5-a]pyrazin-4(5h)-one::US9676782, 71

SMILES C[C@H]1CN(C(=O)c2cc(CNc3cc(F)ccc3F)nn12)c1ccc(F)cc1

InChI Key InChIKey=FFSARCDIJCEKAU-LBPRGKRZSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 196727   

TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt University

US Patent
LigandPNGBDBM196727((s)-2-(((2,5-difluorophenyl)amino)methyl)-5-(4-flu...)
Affinity DataIC50:  9.60E+3nMT: 25°CAssay Description:Gα15/TREx cells stably expressing rat mGlu3 were plated in black-walled, clear-bottomed, poly-D-lysine coated 384-well plates in 20 μL of a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetMetabotropic glutamate receptor 3(Rat)
Vanderbilt University

US Patent
LigandPNGBDBM196727((s)-2-(((2,5-difluorophenyl)amino)methyl)-5-(4-flu...)
Affinity DataIC50:  1.31E+3nMT: 25°CAssay Description:HEK 293A cells stably expressing rat mGlu5 were plated in black-walled, clear-bottomed, poly-D-lysine coated 384-well plates in 20 μL of assay m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent