BDBM19720 (2S)-4,4-dimethyl-2-(morpholin-4-ylcarbonylamino)-N-[(2S)-1-{[4-(trifluoromethoxy)phenyl]amino}propan-2-yl]pentanamide::arylaminoethyl amide deriv. 34

SMILES C[C@@H](CNc1ccc(OC(F)(F)F)cc1)NC(=O)[C@H](CC(C)(C)C)NC(=O)N1CCOCC1

InChI Key InChIKey=MCMLWTOYLYDICJ-YJBOKZPZSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 19720   

TargetCathepsin S(Homo sapiens (Human))
Gnf

LigandPNGBDBM19720((2S)-4,4-dimethyl-2-(morpholin-4-ylcarbonylamino)-...)
Affinity DataKi:  93nM ΔG°:  -9.97kcal/molepH: 5.5 T: 2°CAssay Description:The recombinant human cathepsin enzyme was preincubated with inhibitor for 20 minutes prior to addition of substrate. The substrate hydrolysis was mo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Gnf

LigandPNGBDBM19720((2S)-4,4-dimethyl-2-(morpholin-4-ylcarbonylamino)-...)
Affinity DataKi:  461nMAssay Description:The recombinant human cathepsin enzyme was preincubated with inhibitor for 20 minutes prior to addition of substrate. The substrate hydrolysis was mo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Gnf

LigandPNGBDBM19720((2S)-4,4-dimethyl-2-(morpholin-4-ylcarbonylamino)-...)
Affinity DataKi:  1.46E+4nMAssay Description:The recombinant human cathepsin enzyme was preincubated with inhibitor for 20 minutes prior to addition of substrate. The substrate hydrolysis was mo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed