BDBM197674 US9216981, 2

SMILES Fc1ccc(NS(=O)(=O)c2cccc(c2)C(F)(F)F)c(F)c1Nc1ncccc1-c1ncnc2[nH]cnc12

InChI Key InChIKey=GRPSMJSHOIVSEK-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 197674   

TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Medpacto

US Patent
LigandPNGBDBM197674(US9216981, 2)
Affinity DataEC50:  230nMT: 2°CAssay Description:To check the B-Raf cell activity inhibitory capability of the compounds of the present invention, the following experiments were conducted in A375P...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Medpacto

US Patent
LigandPNGBDBM197674(US9216981, 2)
Affinity DataIC50:  8.80nMpH: 7.2 T: 2°CAssay Description:To check the B-Raf kinase inhibitory activity of the compounds of the present invention, the following experiments were conducted.(1) Serial Signalin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent