BDBM197770 US9216986, 6-[2-(5,8-Dimethyl-[1,2,4]triazolo[1,5-a]pyrazin-2-yl)-ethyl]-2,2-difluoro-[1,3]dioxolo[4,5-g]quinoline

SMILES Cc1cnc(C)c2nc(CCc3ccc4cc5OC(F)(F)Oc5cc4n3)nn12

InChI Key InChIKey=KAWKUSXEOQYISU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 197770   

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A [440-779](Homo sapiens (Human))
H. Lundbeck

US Patent
LigandPNGBDBM197770(US9216986, 6-[2-(5,8-Dimethyl-[1,2,4]triazolo[1,5-...)
Affinity DataIC50:  520nMT: 2°CAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent