BDBM197775 US9216986, 8-Chloro-2-[2-(5,8-dimethyl-[1,2,4]triazolo[1,5-a]pyrazin-2-yl)-ethyl]-6-methyl-quinoline

SMILES Cc1cc(Cl)c2nc(CCc3nc4c(C)ncc(C)n4n3)ccc2c1

InChI Key InChIKey=CIEPFSOSKLIFON-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 197775   

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A [440-779](Homo sapiens (Human))
H. Lundbeck

US Patent
LigandPNGBDBM197775(US9216986, 8-Chloro-2-[2-(5,8-dimethyl-[1,2,4]tria...)
Affinity DataIC50:  290nMT: 2°CAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent