BDBM197965 2-(((4-(difluoromethoxy)-2-fluorophenyl)amino)methyl)-5-(5-fluoropyridin-2-yl)-6,7-dihydropyrazolo[1,5-a]pyrazin-4(5h)-one::US9676782, 146

SMILES FC(F)Oc1ccc(NCc2cc3C(=O)N(CCn3n2)c2ccc(F)cn2)c(F)c1

InChI Key InChIKey=KYLJSCVSHOKZNM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 197965   

TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Vanderbilt University

US Patent
LigandPNGBDBM197965(2-(((4-(difluoromethoxy)-2-fluorophenyl)amino)meth...)
Affinity DataIC50:  3.00E+4nMT: 2°CAssay Description:Gα15/TREx cells stably expressing rat mGlu3 were plated in black-walled, clear-bottomed, poly-D-lysine coated 384-well plates in 20 μL of a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 3(Rattus norvegicus (Rat))
Vanderbilt University

US Patent
LigandPNGBDBM197965(2-(((4-(difluoromethoxy)-2-fluorophenyl)amino)meth...)
Affinity DataIC50:  578nMT: 2°CAssay Description:HEK 293A cells stably expressing rat mGlu5 were plated in black-walled, clear-bottomed, poly-D-lysine coated 384-well plates in 20 μL of assay m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent