BDBM198143 5-(3-(4-Bromophenyl)-1-phenyl-1H-pyrazol-4-yl)-3-(pyridin-3-yl)-4,5-dihydropyrazole-1-carbothioamide (6e)

SMILES NC(=S)N1N=C(CC1c1cn(nc1-c1ccc(Br)cc1)-c1ccccc1)c1cccnc1

InChI Key InChIKey=YXUOUYHCHKNDFJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 198143   

TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
Jamia Millia Islamia (A Central University)

LigandPNGBDBM198143(5-(3-(4-Bromophenyl)-1-phenyl-1H-pyrazol-4-yl)-3-(...)
Affinity DataIC50:  7.03E+5nMpH: 7.9Assay Description:Relaxation of negatively supercoiled plasmid DNA by human topoisomerase IIα was assayed in 20 µL of reaction buffer (10 mM Tris-HCl, pH 7.9, 150...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed