BDBM19841 (1R,2R)-N-(cyanomethyl)-2-[(1,3-thiazol-2-ylsulfanyl)methyl]cyclohexane-1-carboxamide::Cyclohexanecarboxamide derivative, 12y::racemic mixture

SMILES O=C(NCC#N)[C@@H]1CCCC[C@H]1CSc1nccs1

InChI Key InChIKey=NJHHCTDPXYFXAP-WDEREUQCSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 19841   

TargetCathepsin K(Oryctolagus cuniculus (rabbit))
Merck Frosst Centre For Therapeutic Research

LigandPNGBDBM19841((1R,2R)-N-(cyanomethyl)-2-[(1,3-thiazol-2-ylsulfan...)
Affinity DataIC50:  490nMpH: 5.5 T: 2°CAssay Description:Prior to the addition of substrate, different concentrations of the inhibitor ranging from 100 uM to 0.2 nM were preincubated for 15 min with enzyme ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed