BDBM198860 US9221797, 23

SMILES CN1CCN(CC1)C(C)(C)c1ccc(NC(=O)c2nc(c[nH]2)C#N)c(c1)C1=CCC(C)(C)CC1

InChI Key InChIKey=PABZNWOXICIOPN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 198860   

TargetMacrophage colony-stimulating factor 1 receptor [555-568](Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM198860(US9221797, 23)
Affinity DataIC50:  5.10nMpH: 7.5Assay Description:A fluorescence polarization competition immunoassay was used to measure compound inhibition of CSF-1R phosphorylation of tyrosine on a synthetic CS...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMacrophage colony-stimulating factor 1 receptor [555-568](Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM198860(US9221797, 23)
Affinity DataIC50:  2.90nMpH: 7.5Assay Description:A fluorescence polarization competition immunoassay was used to measure compound inhibition of CSF-1R phosphorylation of tyrosine on a synthetic CS...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent