BDBM198921 5-(4-fluorophenyl)-2-(((4-methylpyridin-2-yl)amino)methyl)-6,7-dihydropyrazolo[1,5-a]pyrazin-4(5h)-one::US9676782, 161

SMILES Cc1ccnc(NCc2cc3C(=O)N(CCn3n2)c2ccc(F)cc2)c1

InChI Key InChIKey=OZRYZQIAJKIFQA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 198921   

TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Vanderbilt University

US Patent
LigandPNGBDBM198921(5-(4-fluorophenyl)-2-(((4-methylpyridin-2-yl)amino...)
Affinity DataIC50:  3.00E+4nMT: 2°CAssay Description:Gα15/TREx cells stably expressing rat mGlu3 were plated in black-walled, clear-bottomed, poly-D-lysine coated 384-well plates in 20 μL of a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 3(Rattus norvegicus (Rat))
Vanderbilt University

US Patent
LigandPNGBDBM198921(5-(4-fluorophenyl)-2-(((4-methylpyridin-2-yl)amino...)
Affinity DataIC50:  3.75E+3nMT: 2°CAssay Description:HEK 293A cells stably expressing rat mGlu5 were plated in black-walled, clear-bottomed, poly-D-lysine coated 384-well plates in 20 μL of assay m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent