BDBM19965 6-(4-methanesulfonylphenyl)-5-({4-[2-(piperidin-1-yl)ethoxy]phenyl}methyl)naphthalen-2-ol::LY2066948 analogue, 9

SMILES CS(=O)(=O)c1ccc(cc1)-c1ccc2cc(O)ccc2c1Cc1ccc(OCCN2CCCCC2)cc1

InChI Key InChIKey=FGQKZJQBKCJYLS-UHFFFAOYSA-N

Data  2 KI  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 19965   

TargetEstrogen receptor(Homo sapiens (Human))
Eli Lilly

LigandPNGBDBM19965(6-(4-methanesulfonylphenyl)-5-({4-[2-(piperidin-1-...)
Affinity DataKi:  1.15nM ΔG°:  -12.1kcal/mole EC50:  4.78nMpH: 7.5 T: 2°CAssay Description:The binding affinities were determined by a competitive radiometric binding assay using [3H]estradiol as tracer. The Kd for 3H-estradiol was determin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Eli Lilly

LigandPNGBDBM19965(6-(4-methanesulfonylphenyl)-5-({4-[2-(piperidin-1-...)
Affinity DataKi:  24.1nM ΔG°:  -10.3kcal/mole EC50:  4.78nMpH: 7.5 T: 2°CAssay Description:The binding affinities were determined by a competitive radiometric binding assay using [3H]estradiol as tracer. The Kd for 3H-estradiol was determin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed