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BDBM199939 US9670230, 3

SMILES: CC1CCc2ccc(CCc3nc4c(C)ncc(C)n4n3)nc2N1

InChI Key: InChIKey=GRBBPJZXUBMZMR-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 199939   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A


(Homo sapiens (Human))
BDBM199939
PNG
(US9670230, 3)
Show SMILES CC1CCc2ccc(CCc3nc4c(C)ncc(C)n4n3)nc2N1
Show InChI InChI=1S/C18H22N6/c1-11-4-5-14-6-7-15(21-17(14)20-11)8-9-16-22-18-13(3)19-10-12(2)24(18)23-16/h6-7,10-11H,4-5,8-9H2,1-3H3,(H,20,21)
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MMDB

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PC cid
PC sid
UniChem
US Patent
n/an/a 55n/an/an/an/an/an/a



Sunovion Pharmaceuticals Inc.

US Patent


Assay Description
In one embodiment, the compounds provided herein were assayed for their ability to inhibit human PDE-10A. In one embodiment, the activities of the co...


US Patent US9670230 (2017)


BindingDB Entry DOI: 10.7270/Q2JS9NMV
More data for this
Ligand-Target Pair