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BDBM199964 US9670230, 10

SMILES: CC1COc2ccc(CCc3nc4c(C)ncc(C)n4n3)nc2N1C

InChI Key: InChIKey=QJUQTZWOASXMRJ-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 199964   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A


(Homo sapiens (Human))
BDBM199964
PNG
(US9670230, 10)
Show SMILES CC1COc2ccc(CCc3nc4c(C)ncc(C)n4n3)nc2N1C
Show InChI InChI=1S/C18H22N6O/c1-11-9-19-13(3)17-21-16(22-24(11)17)8-6-14-5-7-15-18(20-14)23(4)12(2)10-25-15/h5,7,9,12H,6,8,10H2,1-4H3
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PC cid
PC sid
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US Patent
n/an/a 300n/an/an/an/an/an/a



Sunovion Pharmaceuticals Inc.

US Patent


Assay Description
In one embodiment, the compounds provided herein were assayed for their ability to inhibit human PDE-10A. In one embodiment, the activities of the co...


US Patent US9670230 (2017)


BindingDB Entry DOI: 10.7270/Q2JS9NMV
More data for this
Ligand-Target Pair