BDBM200307 US9226927, 25b

SMILES Fc1ccc(F)c2c1OCC1[C@H](CCS(=O)(=O)c3cccnn3)OCC[C@@]21S(=O)(=O)c1ccc(Cl)cc1

InChI Key InChIKey=CDOXOSTUKWFFMW-OUSZHMKWSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 200307   

TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM200307(US9226927, 25b)
Affinity DataIC50:  4.5nMpH: 7.0 T: 2°CAssay Description:To measure γ-secretase activity, membranes were incubated at 37° C. for 1 h in 50 μL of buffer containing 20 mM Hepes (pH 7.0) and 2 mM EDT...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent