BDBM200316 US9227956, 1

SMILES Cc1cccnc1N([C@@H]1CCCNC1)C(=O)c1ccc(cc1)-c1cnn2cccnc12

InChI Key InChIKey=BPKFNINHTCLDAF-HXUWFJFHSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 200316   

TargetProprotein convertase subtilisin/kexin type 9(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM200316(US9227956, 1)
Affinity DataIC50:  3.20E+3nMAssay Description:An in-vitro AlphaLISA assay (Perkin Elmer) was developed in order to quantitate the level of PCSK9 secreted into the cell culture media following com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProprotein convertase subtilisin/kexin type 9(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM200316(US9227956, 1)
Affinity DataIC50:  2.20E+3nMAssay Description:Inhibition of PCSK9 translation in human THP-1 cells by AlphaLISA assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProprotein convertase subtilisin/kexin type 9(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM200316(US9227956, 1)
Affinity DataIC50:  440nMAssay Description:In order to eliminate the permeability barrier inherent to the WT7 and SCHH cell-based assays a cell-free system was also established to access compo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent