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BDBM200909 US9233946, 8

SMILES: CC(C)c1ccc2sc(c(C)c2c1)S(=O)(=O)Nc1nc(C)c(s1)C(O)=O

InChI Key: InChIKey=ZQESQZGRGLZODB-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 200909   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 (PFKFB3)


(Homo sapiens (Human))
BDBM200909
PNG
(US9233946, 8)
Show SMILES CC(C)c1ccc2sc(c(C)c2c1)S(=O)(=O)Nc1nc(C)c(s1)C(O)=O
Show InChI InChI=1S/C17H18N2O4S3/c1-8(2)11-5-6-13-12(7-11)9(3)16(24-13)26(22,23)19-17-18-10(4)14(25-17)15(20)21/h5-8H,1-4H3,(H,18,19)(H,20,21)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
n/an/a 610n/an/an/an/an/an/a



KANCERA AB

US Patent


Assay Description
Method A: The kinase activity of the bi-functional enzyme is readily quantified based on the production of F-2,6-P2 as described by Van Schaftingen e...


US Patent US9233946 (2016)


BindingDB Entry DOI: 10.7270/Q2V123KB
More data for this
Ligand-Target Pair