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BDBM200914 US9233946, 13

SMILES: CC(C)c1ccc2oc(c(C)c2c1)S(=O)(=O)Nc1cccc(c1)-c1nnn[nH]1

InChI Key: InChIKey=RLGDHFSWRXNYEM-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 200914   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 (PFKFB3)


(Homo sapiens (Human))
BDBM200914
PNG
(US9233946, 13)
Show SMILES CC(C)c1ccc2oc(c(C)c2c1)S(=O)(=O)Nc1cccc(c1)-c1nnn[nH]1
Show InChI InChI=1S/C19H19N5O3S/c1-11(2)13-7-8-17-16(10-13)12(3)19(27-17)28(25,26)22-15-6-4-5-14(9-15)18-20-23-24-21-18/h4-11,22H,1-3H3,(H,20,21,23,24)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
n/an/a 80n/an/an/an/an/an/a



KANCERA AB

US Patent


Assay Description
Method A: The kinase activity of the bi-functional enzyme is readily quantified based on the production of F-2,6-P2 as described by Van Schaftingen e...


US Patent US9233946 (2016)


BindingDB Entry DOI: 10.7270/Q2V123KB
More data for this
Ligand-Target Pair