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BDBM200959 US9233946, 58

SMILES: NC(=O)c1cccc(c1)-c1ccc(s1)S(=O)(=O)Nc1cccc(c1)-c1nnn[nH]1

InChI Key: InChIKey=XLNJFNBFPKJPPZ-UHFFFAOYSA-N

Data: 1 IC50

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   Substructure
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 200959   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 (PFKFB3)


(Homo sapiens (Human))
BDBM200959
PNG
(US9233946, 58)
Show SMILES NC(=O)c1cccc(c1)-c1ccc(s1)S(=O)(=O)Nc1cccc(c1)-c1nnn[nH]1
Show InChI InChI=1S/C18H14N6O3S2/c19-17(25)12-4-1-3-11(9-12)15-7-8-16(28-15)29(26,27)22-14-6-2-5-13(10-14)18-20-23-24-21-18/h1-10,22H,(H2,19,25)(H,20,21,23,24)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
n/an/a 540n/an/an/an/an/an/a



KANCERA AB

US Patent


Assay Description
Method A: The kinase activity of the bi-functional enzyme is readily quantified based on the production of F-2,6-P2 as described by Van Schaftingen e...


US Patent US9233946 (2016)


BindingDB Entry DOI: 10.7270/Q2V123KB
More data for this
Ligand-Target Pair