BDBM201036 US9540373, 24::US9879026, Example 24::USRE47636, Example 24

SMILES Fc1cc(ccc1C[C@H](NC(=O)[C@H]1N[C@@H]2CC[C@H]1C2)C#N)-c1ccc2C(=O)OC3(CCN(CC3)C3COC3)c2n1

InChI Key InChIKey=QDEUYXRXWLXIES-LMMUWCHVSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 201036   

TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM201036(US9540373, 24 | US9879026, Example 24 | USRE47636,...)
Affinity DataIC50:  2.70nMT: 2°CAssay Description:The recombinant human DPPI was diluted in TAGZyme buffer to 1 U/ml (38.1 μg/ml, respectively), and then activated by mixing in a 1:2 ratio with ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM201036(US9540373, 24 | US9879026, Example 24 | USRE47636,...)
Affinity DataIC50:  2.70nMAssay Description:Materials: Microtiterplates (Optiplate-384 F) were purchased from PerkinElmer (Prod. No. 10 6007270). The substrate Gly-Arg-AMC was from Biotrend (Pr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM201036(US9540373, 24 | US9879026, Example 24 | USRE47636,...)
Affinity DataIC50:  2.70nMT: 2°CAssay Description:Assay conditions: The recombinant human DPPI was diluted in TAGZyme buffer to 1 U/ml (38.1 μg/ml, respectively), and then activated by mixing in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent