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BDBM201406 US9187424, 172

InChI string: InChI=1/C27H26F3N3O5/c1-3-4-15-37-20-11-7-18(8-12-20)26(27(28,29)30)16-21(17-5-9-19(36-2)10-6-17)23(25(35)33-26)32-24(34)22-13-14-31-38-22/h5-14H,3-4,15-16H2,1-2H3,(H,32,34)(H,33,35)

SMILES: CCCCOc1ccc(cc1)C1(CC(=C(NC(=O)c2ccno2)C(=O)N1)c1ccc(OC)cc1)C(F)(F)F

InChI Key: InChIKey=SSHDDTYQNQYBAK-UHFFFAOYNA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 201406   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Monoacylglycerol acyltransferase type 2 (h-MGAT2)


(Homo sapiens (Human))
BDBM201406
PNG
(US9187424, 172)
Show SMILES CCCCOc1ccc(cc1)C1(CC(=C(NC(=O)c2ccno2)C(=O)N1)c1ccc(OC)cc1)C(F)(F)F
Show InChI InChI=1/C27H26F3N3O5/c1-3-4-15-37-20-11-7-18(8-12-20)26(27(28,29)30)16-21(17-5-9-19(36-2)10-6-17)23(25(35)33-26)32-24(34)22-13-14-31-38-22/h5-14H,3-4,15-16H2,1-2H3,(H,32,34)(H,33,35)
UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
AffyNet 
US Patent
n/an/a 16n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
MGAT2 enzyme was assayed using membranes isolated from Sf9 cells expressing the recombinant human MGAT2 cDNA with 2-monooleoylglycerol and [3H]-oleoy...


US Patent US9187424 (2015)

More data for this
Ligand-Target Pair
Monoacylglycerol acyltransferase type 2 (h-MGAT2)


(Homo sapiens (Human))
BDBM201406
PNG
(US9187424, 172)
Show SMILES CCCCOc1ccc(cc1)C1(CC(=C(NC(=O)c2ccno2)C(=O)N1)c1ccc(OC)cc1)C(F)(F)F
Show InChI InChI=1/C27H26F3N3O5/c1-3-4-15-37-20-11-7-18(8-12-20)26(27(28,29)30)16-21(17-5-9-19(36-2)10-6-17)23(25(35)33-26)32-24(34)22-13-14-31-38-22/h5-14H,3-4,15-16H2,1-2H3,(H,32,34)(H,33,35)
UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
AffyNet 
US Patent
n/an/a 3n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The MGAT enzyme reactions were performed in CORNING Falcon 96-well Polypropylene plates, in a total volume of 60 uL of 50 mM Potassium Phosphate buff...


US Patent US9187424 (2015)

More data for this
Ligand-Target Pair