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BDBM201514 US9187424, 281

InChI string: InChI=1/C28H25F6N3O4/c1-16-4-6-18(7-5-16)21-15-26(28(32,33)34,19-8-10-20(11-9-19)40-13-3-12-27(29,30)31)36-25(39)23(21)24(38)35-22-14-17(2)37-41-22/h4-11,14H,3,12-13,15H2,1-2H3,(H,35,38)(H,36,39)

SMILES: Cc1cc(NC(=O)C2=C(CC(NC2=O)(c2ccc(OCCCC(F)(F)F)cc2)C(F)(F)F)c2ccc(C)cc2)on1

InChI Key: InChIKey=MOCRUSFTZZNVHM-UHFFFAOYNA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 201514   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Monoacylglycerol acyltransferase type 2 (h-MGAT2)


(Homo sapiens (Human))
BDBM201514
PNG
(US9187424, 281)
Show SMILES Cc1cc(NC(=O)C2=C(CC(NC2=O)(c2ccc(OCCCC(F)(F)F)cc2)C(F)(F)F)c2ccc(C)cc2)on1
Show InChI InChI=1/C28H25F6N3O4/c1-16-4-6-18(7-5-16)21-15-26(28(32,33)34,19-8-10-20(11-9-19)40-13-3-12-27(29,30)31)36-25(39)23(21)24(38)35-22-14-17(2)37-41-22/h4-11,14H,3,12-13,15H2,1-2H3,(H,35,38)(H,36,39)
UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
AffyNet 
US Patent
n/an/a 3n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The MGAT enzyme reactions were performed in CORNING Falcon 96-well Polypropylene plates, in a total volume of 60 uL of 50 mM Potassium Phosphate buff...


US Patent US9187424 (2015)

More data for this
Ligand-Target Pair