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BDBM201539 US9187424, 306

InChI string: InChI=1/C27H23F10N5O2/c28-19-12-17(8-9-20(19)44-11-3-1-2-10-25(29,30)31)24(27(35,36)37)14-18(21(23(43)38-24)22-39-41-42-40-22)16-6-4-15(5-7-16)13-26(32,33)34/h4-9,12H,1-3,10-11,13-14H2,(H,38,43)(H,39,40,41,42)

SMILES: Fc1cc(ccc1OCCCCCC(F)(F)F)C1(CC(=C(c2nn[nH]n2)C(=O)N1)c1ccc(CC(F)(F)F)cc1)C(F)(F)F

InChI Key: InChIKey=OMFPZTCKKJIQFA-UHFFFAOYNA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 201539   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Monoacylglycerol acyltransferase type 2 (h-MGAT2)


(Homo sapiens (Human))
BDBM201539
PNG
(US9187424, 306)
Show SMILES Fc1cc(ccc1OCCCCCC(F)(F)F)C1(CC(=C(c2nn[nH]n2)C(=O)N1)c1ccc(CC(F)(F)F)cc1)C(F)(F)F
Show InChI InChI=1/C27H23F10N5O2/c28-19-12-17(8-9-20(19)44-11-3-1-2-10-25(29,30)31)24(27(35,36)37)14-18(21(23(43)38-24)22-39-41-42-40-22)16-6-4-15(5-7-16)13-26(32,33)34/h4-9,12H,1-3,10-11,13-14H2,(H,38,43)(H,39,40,41,42)
UniProtKB/SwissProt

antibodypedia
GoogleScholar
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PC cid
PC sid
UniChem
AffyNet 
US Patent
n/an/a 3n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The MGAT enzyme reactions were performed in CORNING Falcon 96-well Polypropylene plates, in a total volume of 60 uL of 50 mM Potassium Phosphate buff...


US Patent US9187424 (2015)

More data for this
Ligand-Target Pair